Nucleic Acid Biochemistry
Department of Biochemistry & Molecular Biology includes a strong group of researchers investigating nucleic acid biochemistry at the molecular level. Using the tools of chemistry, molecular biology, genomics, and structural biology we study catalytic RNA, splicing, RNA folding, RNA modification, DNA recombination and repair, and the ribosome.
Goldwasser, Eugene - ProfessorBiochemistry of blood cell differentiation; mode of action of erythropoietin.
Pan, Tao - ProfessorRNA functional genomics, RNA epigenetics, RNA folding
Piccirilli, Joseph - ProfessorNon-Coding RNA structure, function, and mechanism; RNA metabolism, engineering antibodies that bind RNA, imaging technology for RNA and cancer
Rice, Phoebe - ProfessorWe study mechanisms of DNA recombination and protein-DNA recognition, combining the tools of biochemistry and x-ray crystallography.
Ruthenburg, Alexander - Assistant ProfessorChromatin Biochemistry, Biophysics and Chemical Biology
Sosnick, Tobin - ProfessorProtein and RNA/ribozyme folding; design of light-sensitive allosteric proteins; structure prediction, biological dynamics and thermodynamics as basis for understanding function.
Wool, Ira - ProfessorStructure and function of eukaryotic ribosomes; RNA structures; RNA-protein interaction.