Stephen C Meredith
Research Summary / Selected Publications
Mechanisms of protein aggregation, and structure of amyloid fibrils, especially beta-amyloid fibrils using a combination of solution and solid-state NMR, and other physical methods. Peptide synthesis. Lipoprotein structure and function.
Papers in 2009; Select older papers
Bockhorn JJ, Lazar KL, Gasser A, Luther LM, Qahwash IM, Chopra N, and Meredith SC, Novel Semi-synthetic Method for Generating Full Length β-Amyloid Peptides, submitted, Biopolymers.
Lanning JD and Meredith SC, Chaperone-like N-methyl Peptide Inhibitors of Polyglutamine Aggregation, submitted, Biochemistry.
Paravastu AK, Qahwash IM, Leapman RD, Meredith SC and Tycko R, Seeded growth of synthetic β-amyloid fibrils from Alzheimer’s brain-derived fibrils produces a novel fibril structure, Proc. Natl. Acad. Sci. USA. 106: 7443-7448, 2009
Darnell GD, Derryberry JM, Kurutz JW, and Meredith SC, Flanking Polyprolines Induce Polyglutamine Aggregation as PPII Helices Through the Hydrophobic Effect, Biophys J. 97: 2295-2305, 2009.